When sharing a mosaic dataset as a web tile layer or cached map image layer, the cache may not be generated properly if the number of rows and columns of the maximum image size of requests is set to a value less than 4096 by 4096. A higher value is recommended for improved cache generation.
Solution
Use the Set Mosaic Dataset Properties geoprocessing tool to change the Rows of Maximum Image Size of Requests and Columns of Maximum Image Size of Requests values, under Image Properties, to a value greater than 4096 for an improved cache.
More information
For more information, see Create a mosaic dataset and Analyze your GIS resource.